Acute diarrhea caused by Rotavirus usually has an acute onset, manifesting in children with continuous vomiting and frequent watery diarrhea (usually more than 10 times), up to several dozen times a day, causing severe dehydration, which is a risk of hypovolemic shock, possibly fatal. Rotavirus is one of the major causes of severe and life-threatening diarrhea in children under 2 years of age. The disease usually occurs seasonally, focusing on winter. Rotavirus has 4 pathogenic serotypes. When infected with one type, the body only responds to diarrhea with that one type and the child may still have other types. 1/3 of children under 2 years old have at least 1 episode of rotavirus diarrhea, which also accounts for 50% - 65% of acute diarrhea in hospitalized children.